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隐花色素是植物感受外界环境变化的重要光受体之一,对蓝光和近紫外线非常敏感。近年来随着研究的逐步深入,已知其广泛存在于动植物中。隐花色素为黄素类蛋白,在蓝光和近紫外线下能够抑制植物胚轴、胚芽鞘等伸长,调控植物开花时间;而且对生物钟及气孔开放也起到调节作用,近来还发现隐花色素在感知磁场、细胞凋亡等方面有调节作用。本文综述了隐花色素的分子结构、它所包含的结构域和相应功能以及植物中隐花色素基因家族的成员组成与进化关系,重点在分子水平上介绍了隐花色素的生理功能与作用机制。
Abstract:Cryptochrome is one of the important receptors in the plants responding to environmental signals,sensing to blue light and UV-A.In the recent years,profound studies have been carried around the cryptochrome.Cryptochrome was not only in plants,but also in animals.Cryptochrome which was flavin-type protein played an important role in inhibition hypocotyl or coleoptile elongation in blue light and UV-A,and in regulation flowering time,circadian clocks and stomatal opening.The function of cryptochrome in magnetoreception,execution of programmed cell death has been found lately.This paper summarized molecular structure of cryptochrome,its domain and function,and the member and relation in evolution of photolyase/cryptochrome family.Physiological function and mechanism of cryptochrome in molecular level were reviewed especially.
Ahmad M.,and Cashmore A.R.,1993,HY4gene of A.thalianaencodes a protein with characteristics of a blue-light pho-toreceptor,Nature,366:162-166
Ahmad M.,Galland P.,Ritz T.,Wiltschko R.,and Wiltschko W.,2007,Magnetic intensity affects cryptochrome-dependentresponses in Arabidopsis thaliana,Planta,225(3):615-624
Ahmad M.,Jarillo J.A.,Smirnova O.,and Cashmore A.R.,1998,The CRY1blue light photoreceptor of Arabidopsis interactswith phytochrome a in vitro,Mol.Cell,1(7):939-948
Ahmad M.,Lin C.,and Cashmore A.R.,1995,Mutationsthroughout an Arabidopsis blue-light photoreceptor impairblue-light-responsive anthocyanin accumulation and inhibi-tion of hypocotyl elongation,Plant J.,8(5):653-658
Bagnall D.J.,King R.W.,and Hangarter R.P.,1996,Blue-lightpromotion of flowering is absent in hy4mutants of Ara-bidopsis,Planta,200(2):278-280
Brautigam C.A.,Smith B.S.,Ma Z.,Palnitkar M.,Tomchick D.R.,Machius M.,and Deisenhofer J.,2004,Structure of the pho-tolyase-like domain of cryptochrome1from Arabidopsisthaliana,Proc.Natl.Acad.Sci.,USA,101(33):12142-12147
Brudler R.,Hitomi K.,Daiyasu H.,Toh H.,Kucho K.,Ishiura M.,Kanehisa M.,Roberts V.A.,Todo T.,Tainer J.A.,and Get-zoff E.D.,2003,Identification of a new cryptochrome class,structure,function,and evolution,Mol.Cell,11(1):59-67
Canamero R.C.,Bakrim N.,Bouly J.P.,Garay A.,Dudkin E.E.,Habricot Y.,and Ahmad M.,2006,Cryptochrome photore-ceptors cry1and cry2antagonistically regulate primary rootelongation in Arabidopsis thaliana,Planta,224(5):995-1003
Cashmore A.R.,Jarillo J.A.,Wu Y.J.,and Liu D.M.,1999,Cryp-tochromes:blue light receptors for plants and animals,Sci-ence,284(5415):760-765
Cashmore A.R.,2003,Cryptochromes:enabling plants and ani-mals to determine circadian time,Cell,114(5):537-543
Danon A.,Coll N.S.,and Apel K.,2006,Cryptochrome-1-de-pendent execution of programmed cell death induced by sin-glet oxygen in Arabidopsis thaliana,Proc.Natl.Acad.Sci.,USA,103(45):17036-17041
Dolezelova E.,Dolezel D.,and Hall J.C.,2007,Rhythm defectscaused by newly engineered null mutations in drosophila'scryptochrome gene,Genetics,177(1):329-345
Dunlap J.C.,1999,Molecular bases for circadian clocks,Cell,96(2):271-290
Gressel J.,1979,Blue light photoreception,Photochem.Photobiol.,30:749-754
Guo H.,Duong H.,Ma N.,and Lin C.,1999,The Arabidopsisblue light receptor cryptochrome2is a nuclear protein regu-lated by a blue light-dependent post-transcriptional mecha-nism,Plant J.,19(3):279-287
Guo H.W.,Yang H.Y.,Mockler T.C.,and Lin C.T.,1998,Regu-lation of flowering time by Arabidopsis photoreceptors,Sci-ence,279(5355):1360-1363
Hirose F.,Shinomura T.,Tanabata T.,Shimada H.,and Takano M.,2006,Involvement of rice cryptochromes in de-etiolation re-sponses and flowering,Plant Cell Physiol.,47(7):915-925
Johnsen S.,Mattern E.,and Ritz T.,2007,Light-dependent mag-netoreception:quantum catches and opponency mechanismsof possible photosensitive molecules,J.Exp.Biol.,210:3171-3178
Kang X.,and Ni M.,2006,Arabidopsis short hypocotyl underblue1contains SPX and EXS domains and acts in cryp-tochrome signaling,Plant Cell,18(4):921-934
Klar T.,Pokorny R.,Moldt J.,Batschauer A.,and Essen L.O.,2007,Cryptochrome3from Arabidopsis thaliana:structuraland functional analysis of its complex with a folate light an-tenna,J.Mol.Biol.,366(3):954-964
Kleine T.,Kindgren P.,Benedict C.,Hendrickson L.,and Strand魡.,2007,Genome-wide gene expression analysis reveals a criti-cal role for CRYPTOCHROME1in the response of Ara-bidopsis to high irradiance,Plant Physiol.,144:1391-1406
Koornneef M.,Rolff E.,and Spruit C.J.P.,1980,Genetic controlof light-inhibited hypocotyl elongation in Arabidopsisthaliana(L.)Heynh,Z.Pflanzenphysiol.,100:147-160
Lin C.,Ahmad M.,and Cashmore A.R.,1996,Arabidopsis cryp-tochrome1is a soluble protein mediating blue light-depen-dent regulation of plant growth and development,Plant J.,10(5):893-902
Lin C.,Ahmad M.,Gordon D.,and Cashmore A.R.,1995a,Ex-pression of an Arabidopsis cryptochrome gene in transgenictobacco results in hypersensitivity to blue,UV-A,and greenlight,Proc.Natl.Acad.Sci.,USA,92(18):8423-8427
Lin C.,Robertson D.E.,Ahmad M.,Raibekas A.A.,Jorns M.S.,Dutton P.L.,and Cashmore A.R.,1995b,Association offlavin adenine dinucleotide with the Arabidopsis blue lightreceptor CRY1,Science,269(5226):968-970
Lin C.T.,Yang H.Y.,Guo H.W.,Mockler T.,Chen J.,and CashmoreA.R.,1998,Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome2,Proc.Natl.Acad.Sci.,USA,95(5):2686-2690
Lin C.T.,2000,Plant blue-light receptors,Trends Plant Sci.,5(8):337-342
Malhotra K.,Kim S.T.,Batschauer A.,Dawut L.,and Sancar A.,1995,Putative blue-light photoreceptors from Arabidopsisthaliana and Sinapis alba with a high degree of sequence ho-mology to DNA photolyase contain the two photolyase co-factors but lack DNA repair activity,Biochemistry,34(20):6892-6899
Mao J.,Zhang Y.C.,Sang Y.,Li Q.H.,and Yang H.Q.,2005,Arole for Arabidopsis cryptochromes and COP1in the regula-tion of stomatal opening,Proc.Natl.Acad.Sci.,USA,102(34):12270-12275
Mockler T.C.,Guo H.,Yang H.,Duong H.,and Lin C.,1999,Antagonistic actions of Arabidopsis cryptochromes and phy-tochrome B in the regulation of floral induction,Develop-ment,126(10):2073-2082
Park H.W.,Kim S.T.,Sancar A.,and Deisenhofer J.,1995,Crystalstructure of DNA photolyase from Escherichia coli,Science,268(5219):1866-1872
Pokorny R.,Klar T.,Essen L.O.,and Batschauer A.,2005,Crys-tallization and preliminary X-ray analysis of cryptochrome3from Arabidopsis thaliana,Struct Biol.Cryst.Commun.,61(10):935-938
Selby C.P.,and Sancar A.,2006,A cryptochrome/photolyase classof enzymes with single-stranded DNA-specific photolyaseactivity,Proc.Natl.Acad.Sci.,USA,103(47):17696-17700
Solovyov I.A.,Chandler D.E.,and Schulten K.,2007,Magneticfield effects in Arabidopsis thaliana cryptochrome-1,Bio-phys J.,92(8):2711-2726
Somers D.E.,Devlin P.F.,and Kay S.A.,1998,Phytochromesand cryptochromes in the entrainment of the Arabidopsis cir-cadian clock,Science,282(5393):1488-1490
Stanewsky R.,Kaneko M.,Emery P.,Beretta B.,Wager-Smith K.,Kay S.A.,Rosbash M.,and Hall J.C.,1998,The cry muta-tion identifies cryptochrome as a circadian photoreceptor inDrosophila,Cell,95(5):681-692
ThresherR.J.,Vitaterna M.H.,Miyamoto Y.,Kazantsev A.,Hsu D.S.,Petit C.,Selby C.P.,Dawut L.,Smithies O.,Takahashi J.S.,and Sancar A.,1998,Role of mouse cryptochrome blue-lightphotoreceptor in circadian photoresponses,Science,282(5393):1490-1494
Todo T.,1999,Functional diversity of the DNA photolyase/bluelight receptor family,Mutat Res.,434(2):89-97
Wu G.,and Spalding E.P.,2007,Separate functions for nuclearand cytoplasmic cryptochrome1during photomorphogene-sis of Arabidopsis seedlings,Proc.Natl.Acad.Sci.,USA,104(47):18813-18818
基本信息:
中图分类号:Q946
引用信息:
[1]朱春利,张桂荣,蔡爱军,等.植物隐花色素结构与功能研究进展[J].基因组学与应用生物学,2009,28(01):174-178.
基金信息:
河北省自然基金(303451);; 河北科技师范学院博士基金资助
2009-02-28
2009-02-28