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为了了解大学生运动员体型与胰岛素敏感度的相关性,我们招募了320名大学生运动员与300名非运动员为受试对象,测量了其身高、体重、BIA体脂肪率,计算身体质量指数(body mass index,BMI),并检测理论空腹血糖、血清胰岛素、稳态模型评估(homeostasis model assessment,HOMA)值、糖化血红蛋白以及胆固醇数值。我们比较了大学生运动员和非运动员胰岛素敏感度与代谢指标,并推测了其关联性。研究发现,运动员的体重、身体质量指数与BIA脂肪率均显著的高于非运动员;运动员的空腹胰岛素以及HOMA都显著的高于非运动员。另以皮尔逊积差相关以及偏相关探讨与胰岛素相关的因子,发现无论有没有经过性别与年龄的校正,运动员或非运动员的肥胖指标(体重,身体质量指数与脂肪率)都与胰岛素敏感度指标(胰岛素,HOMA)呈显著正相关,说明大学生运动员具有较低的胰岛素敏感度,并且胰岛素敏感度随着肥胖指标的升高而下降。本研究结果为揭示运动员体型与胰岛素敏感度的相关性提供了一定的帮助。
Abstract:In order to understand the correlation between body shape and insulin sensitivity of university athletes,320 college athletes and 300 non-athletes were recruited as our subjects, and their indices of body composition(height, weight, bioelectrical impedance analysis(BIA) and body mass index(BMI)) and glucose metabolism regulators(fasting glucose, serum insulin, HOMA, Hb A1 c and cholesterol) were measured. We compared the insulin sensitivity and metabolic indices of university athletes and non-athletes, andspeculated their correlation.We found that the body weights, BMI and BIA of athletes were higher than those of non-athletes. In addition,fasting insulin and HOMA were significantly higher in athletes than thosein non-athletes. Besides, Pearson product-moment correlation and partial correlation were used to assess whether markers of body composition were associated with insulin sensitivity. Here we found obesity levels(body weight, BMI and fat percentage) were correlated with insulin sensitivity(insulin, HOMA and cholesterol) in both athletes and non-athlete groups no matter the gender and age had been adjusted or not. These results demonstrated that university athletes had lower insulin sensitivity, and the insulin sensitivity went down as the obesity levels went up. Our research provided some help for the reveal of correlation between athletes body shape and insulin sensitivity.
Buell J.L.,Calland D.,Hanks F.,Johnston B.,Pester B.,Sweeney R.,and Thorne R.,2008,Resence of metabolic syndrome in football linemen,Journal of Athletic Training,43:608-616
Chen Y.H.,Bi Y.F.,Zhang L.Z.,Hu R.M.,Zhao Y.J.,and Ning G.,2004,Change of insulin sensitivity in obesity subjects and diabetes patients,Zhonghua Neifenmi Daixie Zazhi(Chinese Journal of Endocrinology and Metabolism),20(3):213-214(陈宇红,毕宇芳,张连珍,胡仁明,赵咏桔,宁光,2004,肥胖者与糖尿病患者胰岛素敏感性的变化,中华内分泌代谢杂志,20(3):213-214)
Choate N.,Forster C.,Almquist J.,Olsen C.,and Poth M.,2007,The prevalence of overweight in participants in high school extramural sports,Journal of Adolescent Health,40:283-285
Dankner R.,Chetrit A.,Shanik M.H.,Raz I.,and Roth J.,2009Basal-state hyperinsulinemia in healthy normoglycemic adults is predictive of type 2 diabetes over a 24-year follow-up,Diabetes Care.,32:1464-1466
Duncan G.E.,Perri M.G.,Theriaque D.W.,Hutson A.D.,Eckel R.H.and Stacpoole P.W.,2003,Exercise training,without weigh loss,increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults,Diabetes Care26:557-562
Earnest C.P.,2008,Exercise interval training:an improved stimulus for improving the physiology of pre-diabetes,Medical Hypotheses,2008,71:752-761
Garnett S.P.,Srinivasan S.,Birt S.G.,Ambler G.R.,Lawrie E.A.Cowell C.T.,and Craig M.E.,2010,Evaluation of glycaemic status in young people with clinical insulin resistance;fasting glucose,fasting insulin or an oral glucose tolerance test,Clinical Endocrinology,72:475-480
Garry J.P.,and Mc Shane J.J.,2001,Analysis of lipoproteins and body mass index in professional football players,Preventive Cardiology,4:103-108
Kramer C.K.,Araneta M.R.G.,and Barrett Connor E.,2010,A1Cand diabetes diagnosis:The Rancho Bernardo study,Diabetes Care,33:101-103
Li B.,Liu L.B.,Liu X.Y.,and Wang Y.P.,2005,Effect of moderate-intensityexercise on the insulin sensitivity and plasma level of adiponectin in obese patients with type 2 diabetes mellitus,Zhongguo Zuzhi Gongcheng Yanjiu(Chinese Journal of Tissue Engineering Research),9(39):22-24(李斌,刘礼斌,刘小莺,王燕萍,2005,中等强度运动对2型糖尿病伴肥胖患者胰岛素敏感性及血浆脂联素水平的影响,中国组织工程研究,9(39):22-24)
Li L.M.,Yang Z.Y.,Wei Y.,Xu B.H.,Gao H.,Zhou L.L.,Wang Q.R.and Fang Z.L.,2005,Research on mechanism and rules of pro-glycogen and marco-glycogen repletion in skeletal muscle after exercise,Tiyu Kexue(China Sport Science),25(7)25-30(李良鸣,杨则宜,魏源,许葆华,高红,周丽丽,王启荣方子龙,2005,运动后前糖原和大糖原的恢复规律及其机制研究,体育科学,25(7):25-30)
Li Q.Y.,Chen Z.,Zhang S.Z.,Song Y.T.,Chen N.,and Yu J.,2015Study of blood lipid metabolism and insulin resistance in 126cases of patients with alzheimer's disease,Zhonghua Quanke Yixue(Chinese Journal of General Practice),13(1):15-17,99(李钦云,陈峥,张守字,宋岳涛,陈楠,于佳,2015,126例阿尔茨海默病患者血脂代谢和胰岛素抵抗的研究,中华全科医学,13(1):15-17,99)
Li X.C.,Shi L.,Ren W.D.,and Zhu X.B.,2017,Improvement of insulin sensitivity by osteocalcin inhibits inflammation in the adipose tissue of obese mice,Zhongguo Bingli Shengli Zazhi(Chinese Journal of Pathophysiology),33(2):302-307(李小成,史丽,任卫东,朱晓波,2017,骨钙素通过抑制脂肪组织炎症改善肥胖小鼠胰岛素敏感性,中国病理生理杂志,33(2):302-307)
Liang X.L.,2001,Quantitative detection for the sensitivity of insulin,Yixue Yanjiu Zazhi(Journal of Medical Research),30(2):28-30(梁兴伦,2001,胰岛素敏感性定量检测,医学研究杂志,30(2):28-30)
Lippi G,Montagnana M.,Salvagno G.L.,Franchini M.,and Guidi G.C.,2008,Glycaemic control in athletes,International Journal of Sports Medicine,29(1):7-10
Little R.R.,and Sacks D.B.,2009,Hb A1c:How do we measure it and what does it mean,Current Opinion in Endocrinology,Diabetes and Obesity,16(2):113-118
Liu J.,Cha Y.,Sheng L.,Chen Z.P.,Chen Q.D.,Liao X.H.,Wu Q.,and Meng L.P.,2006,Changes of beta-cell function and insulin sensitivity in abdominal visceral obesity,Fudan Xuebao(Yixue Ban)(Fudan University Journal of Medical Sciences),33(3):393-396(刘军,查英,盛励,陈灶萍,陈钦达,廖晓寰,吴强,孟令平,2006,腹型肥胖患者胰岛β细胞功能和胰岛素敏感性的变化,复旦学报(医学版),33(3):393-396)
Mc Hugh M.,2009,Oversized young athletes:a weighty concern,British Journal of Sports Medicine,44:45-49
Ode J.J.,Pivarnik J.M.,Reeves M.J.,and Knous J.L.,2007,Body mass index as a predictor of percent fat in college athletes and nonathletes,Medicine and Science in Sports and Exercise,39:403-409
Sun Y.,2006,Exercise and insulin sensitivity,Zhongguo Zuzhi Gongcheng Yanjiu(Chinese Journal of Tissue Engineering Research),10(44):167-169(孙焱,2006,运动与胰岛素的敏感性,中国组织工程研究,10(44):167-169)
Yamamoto J.B.,Yamamoto B.E.,Yamamoto P.P.,and Yamamoto L.G.,2008,Epidemiology of college athlete sizes,1950s to current,Research in Sports Medicine,16(2):111-127
基本信息:
DOI:10.13417/j.gab.036.004023
中图分类号:G804.49
引用信息:
[1]郭林.大学生运动员体型与胰岛素敏感度相关性研究[J].基因组学与应用生物学,2017,36(10):4023-4029.DOI:10.13417/j.gab.036.004023.
基金信息:
陕西省社会科学基金项目(陕西全民健身活动状况调查与建设研究)(2016Q026)资助
2017-10-25
2017-10-25