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2016, 01, v.35 34-37
天然药物抗甲型流感病毒的研究进展
基金项目(Foundation): 贵州省科技厅项目(No.:LH[2014]7563);; 遵义医学院博士启动基金(NOZMKD2013-006)共同资助
邮箱(Email):
DOI: 10.13417/j.gab.035.000034
发布时间: 2016-01-25
出版时间: 2016-01-25
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摘要:

甲流是一种由病毒感染引起的急性呼吸道传染病,具有致病性高、传染性强等特点,曾在世界范围内多次大流行,困扰人们的日常生活甚至威胁身体健康。伴随着现代药物分离、纯化技术的发展,天然药物的活性成分研究为新药开发带来了第二个春天,也使天然药物抗流感病毒引起越来越多的关注,本综述总结大量研究成果,阐明了利用天然药物进行抗流感病毒研究的可行性与有效性,为进一步开发、利用天然药物提供依据。

Abstract:

The influenza A virus is a kind of acute respiratory infectious disease caused by viral infection, has the characteristics of highly pathogenic, strong infectious, has repeatedly caused a worldwide pandemic, serious impact on people with life and health. Along with the development of modern drug separation and purification technology, natural medicine, the active ingredient research for new drug development has brought the second spring, also make the natural medicine against the flu virus to cause the attention of more and more, this review summarizes a large number of research results, illuminates the use of natural drugs for influenza virus research the feasibility and effectiveness of, provide the basis for further development and utilization of natural medicine.

参考文献

Brownstein J.S.,Freifeld C.C.,and Madoff L.C.,2009,Influenza a(H1N1)virus,2009-online monitoring,N.Engl.J.Med.,360(21):2156

Coombes R.,2009,A/H1N1 influenza:questions and answers,BMJ,338(7703):1104-1105

Fen X.,Wang M.,Zhao Y.Y.,Shan Y.,and Dong Y.F.,2002,Effects of total flavonoid from the aerial part of Bupleurum chinense DC.on infected mice by influenza virus,Zhiwu Ziyuan Yu Huanjing Xuebao(Journal of Plant Resources and Environment),11(4):15-18(冯煦,王鸣,赵友谊,单宇,董云发,2002,北柴胡茎叶总黄酮抗流感病毒的作用,植物资源与环境学报,11(4):15-18)

Li J.Q.,Zhang F.X.,Fu L.C.,Hu X.L.,and Zhu Y.T.,2003,Study of effect of Shengjiangsan(SJS)on inhibiting influenza virus A in vivo and in vitro,Zhongyi Yaoxuekan(Study Journal of Traditional Chinese Medicine),21(2):217-218(李际强,张奉学,符林春,胡溪柳,朱宇同,2003,升降散在体外抗甲型流感病毒的作用与对病毒血凝滴度的影响,中医药学刊,21(2):217-218)

Li W.,Wang S.J.,Yan M.,Fu J.H.,and Xie H.X.,1999,Observation of the inhibitory effect of extracts from Houttarnia Cordta Thurb on IFVA,IFVB,MPV,Yufang Yixue Wenxian Xinxi(Liferatue and Information on Preventine Medicine),5(4):347-348(李文,王少军,严敏,傅继华,谢红霞,1999,鱼腥草提取液抗流感,腮腺炎病毒效果观察,预防医学文献信息,5(4):347-348)

Liu P.M.,Zhang H.C.,and Bao P.R.,2001,Experimental study on anti-influenza virus infection with Shengjiang powder,Shandong Zhongyiyao Daxue Xuebao(Journal of Shandong University of Traditional Chinese Medicine),25(01):43-45(刘培民,张鸿彩,包培蓉,2001,升降散抗流感病毒实验研究,山东中医药大学学报,25(01):43-45)

Liu S.,Chen W.S.,Qiao C.Z.,Zheng S.Q.,Zeng M.,Zhang H.M.,and Song Z.J.,2000,Antiviral action of Radix lsatidis and Folium lsatidis from different germplasm against influenza A virus,Dier Junyi Daxue Xuebao(Academic Journal of Second Military Medical University),21(3):204-206(刘盛,陈万生,乔传卓,郑水庆,曾明,张汉明,宋赵军,2000,不同种质板蓝根和大青叶的抗甲型流感病毒作用,第二军医大学学报,21(3):204-206)

Lu F.G.,Tian D.F.,Zhu Y.W.,Wu C.R.,Huang L.Z.,and Tang X.M.,2005,Maxingganshi Jiaweifang for the effects of type A influenza virus infection the immune function of mice,Zhongyiyao Xuebao(Acta Chinese Medicine and Pharmacology),33(2):36-37(卢芳国,田道法,朱应武,伍参荣,黄立中,唐小梅,2005,麻杏甘石汤加味方对A型流感病毒感染小鼠免疫功能的影响,中医药学报,33(2):36-37)

Sun J.,Wang N.R.,Chen S.J.,Li P.,and Tian L.H.,2003,Inhibitory effects of Chuanhuning on the apoptosis induced by influenza virus in MDCK cells,Zhongguo Yiyuan Yaoxue Zazhi(Chinese Journal of Hospital Pharmacy),23(7):405-407(孙坚,王农荣,陈世件,李平,田丽华,2003,穿琥宁抑制流感病毒诱导狗肾传代细胞凋亡,中国医院药学杂志,23(7):405-407)

Tan J.F.,Huang W.W.,Li S.H.,Xu J.,Huang X.Q.,and Zhu B.L.,2001,Study on the pharmacodynamics of Kangbingdu oral liquid,Zhongguo Yaoke Daxue Xuebao(Journal of China Pharmaceutical University),32(05):388-391(谭家风,黄薇薇,李三红,徐进,黄小青,朱宝力,2001,抗病毒口服液药效学研究,中国药科大学学报,32(05):388-391)

Wang W.,Song L.L.,Song D.G.,Li Q.,and Meng Q.G.,2011,Experimental study on anti-influenza virus effect of extracted Scutellaria and effective integridents,Zhonghua Zhongyiyaoxuekan(Chinese Archives of Traditional Chinese Medicine),29(4):710-712(王雯,宋琳莉,宋旦哥,李强,孟庆刚,2011,黄芩提取物与有效成分抗亚洲甲型流感病毒作用的实验研究,中华中医药学刊,29(4):710-712)

Weng L.,Liu Y.,Liu X.Y.,Zhang Y.,Zhao L.A.,and Deng Y.L.,2003,Astragalus polysaccharides powder injection to the little mouse spleen cells Cytokines and the ability of NKkiller,Zhongyiyaoxuekan(Study Journal of Traditional Chinese Medicine),21(9):1522-1524(翁玲,刘彦,刘学英,张颖,赵林爱,邓筱玲,2003,黄芪多糖粉针剂对小鼠脾细胞分泌细胞因子及NK杀伤能力的影响,中医药学刊,21(9):1522-1524

Zhang H.Y.,Wang X.F.,Wang S.Y.,Dong D.,and Hu N.N.,2014,Influence of Yinqiao-powder prescriptions on TLR4and NF-κB p65 in lung tissue of rat models with influenza viral pneumonia,Shizhen Guoyi Guoyao(Lishizhen Medicine and Materia Medica Research),25(10):2321-2323(张海婴,王雪峰,王思源,董丹,胡楠楠,2014,银翘散提取物对流感病毒性肺炎小鼠组织TLR4及NF-κB p65的影响,时珍国医国药,25(10):2321-2323)

Zhang Z.H.,Wang S.C.,Wang R.J.,Wu S.H.,Wang C.H.,and Hu Y.B.,1997,Influence on rabbit fever model and antiviral action of two kinds of Maxingshigan decotum extract,Disi Junyidaxue Xuebao(Journal of the Fourth Military Medical University),18(6):522-524(张仲海,王胜春,王汝娟,吴少华,王长海,胡永武,1997,麻杏石甘汤不同方法提取液对家兔发热模型及抗病毒作用的影响,第四军医大学学报,18(6):522-524)

Zuo L.,Yang X.,Yu X.L.,and Li Y.N.,1997,Astragalus membranaceus part A6 of influenza virus inhibition experiment,Guizhou Yiyao(Guizhou Medical Journal),21(5):272-273(左丽,杨夏,余晓玲,李永念,1997,黄芪A6组分对流感病毒抑制作用的实验研究,贵州医药,21(5):272-273)

基本信息:

DOI:10.13417/j.gab.035.000034

中图分类号:R285

引用信息:

[1]许朋,余兰.天然药物抗甲型流感病毒的研究进展[J].基因组学与应用生物学,2016,35(01):34-37.DOI:10.13417/j.gab.035.000034.

基金信息:

贵州省科技厅项目(No.:LH[2014]7563);; 遵义医学院博士启动基金(NOZMKD2013-006)共同资助

发布时间:

2016-01-25

出版时间:

2016-01-25

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